PQQ: The Dark Horse of Skin Anti-Aging

05 Apr 2025
8

What is PQQ?


PQQ is a new type of coenzyme, limitedly distributed in nature (such as in fermented soybeans (natto), tea, breast milk, etc.). Currently, PQQ can mainly be extracted from some microbial fermentation products and certain plants.


In 1979, Japanese chemist Tatsuo Sakamoto, while conducting similar research, used a new extraction method to extract PQQ from a fermented food (Amami Ōshima's black vinegar). In the late 1980s, it was discovered that PQQ is not only an antioxidant but also stimulates the growth and metabolism of microorganisms and promotes cell energy production. These findings garnered widespread attention in the scientific community.


Biological functions of PQQ


The biological functions of PQQ primarily focus on two main aspects: firstly, it acts like a mitochondrial vitality booster, supporting the growth and development of mitochondria and stimulating rapid growth of human cells. Secondly, it has excellent antioxidant properties, helping to eliminate free radicals and reduce cell damage. These two functions enable it to play a powerful role in brain health, cardiovascular health, and metabolic function health.


In the skincare field, PQQ has strong antioxidant properties that effectively eliminate free radicals, delay skin aging, and promote collagen production to enhance skin elasticity and improve skin texture. Additionally, some studies suggest that it may promote skin repair and regeneration, including accelerated wound healing, reduced inflammatory responses, and increased self-repair capabilities of the skin.


The most important functions of PQQ


Antioxidation


  • Directly eliminating free radicals: PQQ has a special chemical structure that can directly react with free radicals, converting them into relatively stable substances. Free radicals are one of the main factors causing skin aging, including superoxide anion radicals and hydroxyl radicals. PQQ can quickly capture these free radicals, reducing their oxidative damage to skin cells.


  • Activating antioxidant enzyme systems: PQQ can activate intracellular antioxidant enzyme systems, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx). These antioxidant enzymes can catalyze the decomposition of free radicals, reducing oxidative stress levels. By increasing the activity of antioxidant enzymes, PQQ enhances the skin's own antioxidant defense capabilities.


  • Maintaining mitochondrial function: Mitochondria are the energy factories within cells and are also the main production sites for free radicals. PQQ can protect the structural and functional integrity of mitochondria, improving the energy production efficiency of mitochondria and reducing free radical leakage. This helps maintain normal cell metabolism and function, protecting skin cells from oxidative damage.


Promoting collagen production


  • Activating collagen synthesis signaling pathways: PQQ can activate signaling pathways related to collagen production, such as the transforming growth factor-beta (TGF-β) signaling pathway. TGF-β can stimulate fibroblasts to synthesize collagen, increasing skin elasticity and firmness. PQQ promotes collagen synthesis by activating the TGF-β signaling pathway.


  • Regulating collagen-degrading enzyme activity: PQQ can also regulate the activity of collagen-degrading enzymes such as matrix metalloproteinases (MMPs). MMPs degrade collagen, leading to loss of skin elasticity and firmness. PQQ can inhibit the activity of MMPs, reducing collagen degradation, and maintaining collagen content in the skin.


Repair and regeneration


  • Promoting cell proliferation and differentiation: PQQ can promote the growth and differentiation of keratinocytes, fibroblasts, and other cells, facilitating the formation of new skin tissue.


  • Regulating inflammatory response: PQQ can inhibit the production of pro-inflammatory factors such as tumor necrosis factor-alpha (TNF-α) and interleukin-1 beta (IL-1β), while promoting the secretion of anti-inflammatory factors such as interleukin-10 (IL-10). This helps reduce inflammation-induced skin damage and promotes wound healing.


  • Enhancing skin's self-repair capabilities: PQQ can promote DNA repair, reducing DNA damage caused by factors like UV radiation and environmental pollution. Additionally, PQQ can regulate the cell cycle, promoting apoptosis and clearance of damaged cells, creating space for new cell growth.


With the continuous improvement of production capacity and further exploration of application value, PQQ powder, as a unique health ingredient, is gradually gaining widespread market attention. PQQ has shown remarkable effects in promoting cellular energy metabolism, antioxidation, and skin anti-aging, making it an important choice for enhancing overall health levels. With the growing industry demand, PQQ powder will become a key driving force for enterprises to expand into new blue oceans of the health industry. Seizing this opportunity, professional PQQ supplier Natural Field's PQQ powder is undoubtedly your ideal choice for health product innovation, helping enterprises usher in a new era of health and wealth.

Rigorous Standard
Stable Quality
Fast Delivery
Contact Us
Brand Network:
0
Inquire Basket
Empty
Inquiry
0
We use cookies to offer you a better browsing experience, analyze site traffic and personalize content. By using this site, you agree to our use of cookies. Visit our cookie policy to learn more.
Reject Accept